Effect of Fetal Choroid Plexus Cysts on Middle Cerebral Artery Doppler Parameters
Article Language: EN
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Objective: To investigate the possible effects of isolated fetal choroid plexus cysts (CPCs) on middle cerebral artery (MCA) Doppler parameters. Material and Methods: A total of 113 pregnant women at 18 to 22 gestational weeks in whom level 2 ultrasonography (USG) was performed between August 2017 and January 2018 were included in the study. Fifty-five women (CPC group) had isolated fetal CPC, whereas 58 women (control group) had no fetal structural anomaly. We measured the following MCA Doppler parameters of fetuses: peak systolic velocity (PSV), enddiastolic velocity (EDV), the systolic/diastolic ratio (S/D), pulsatility index (PI), and resistance index (RI). We examined whether a significant difference exist between the CPC and control groups, and between the CPC and contralateral sides with respect to the Doppler parameters. Results: We found that cysts were present in the right lateral ventricle in 49.1% (n = 27) individuals in the CPC group (p = 0.037). There was no statistically significant difference between the groups in terms of PSV, EDV, PI and RI values (p > 0.05); however, the S/D ratio exhibited statistical significance (p = 0.021). The MCA S/D ratio of the control group was lower than that of the values reported for both cystic and contralateral sides in the CPC group (p = 0.029 and p = 0.026, respectively). Moreover, we did not observe any significant difference in S/D ratios between the cystic and contralateral sides in the CPC group (p = 0.937). Conclusion: Isolated fetal CPCs tend to occur more on the right side unilaterally. At 18 to 22 weeks of gestation, MCA S/D ratios of the cystic and contralateral sides in the CPC group were higher than that in the control group.
Keywords: Choroid plexus cyst; middle cerebral artery; Doppler ultrasonography; fetus