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Multiple Myeloma-Associated Amyloidosis Mimicking Peritoneal Carcinomatosis: An Unusual Case Report
Received: 19 Jun 2019 | Received in revised form: 04 Jul 2019
Accepted: 04 Jul 2019 | Available online: 05 Sep 2019
J Clin Obstet Gynecol. 2019;29(3):116-9
DOI: 10.5336/jcog.2019-70220
Article Language: EN
Article Language: EN
Copyright Ⓒ 2020 by Türkiye Klinikleri. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Amyloidosis is a disease caused by extracellular deposition of fibrous protein in various tissues and organs. It coexists with multiple myeloma in approximately 12%-15% of cases. Omental amyloidosis is rare. We report a 61-year-old woman with omental amyloidosis associated with multiple myeloma. She presented initial symptoms including abdominal ascites and pleural effusion. The patient was diagnosed as having peritoneal carcinomatosis with elevated CA125 level at the first evaluation. Exploratory laparotomy was performed and the histopathological examination revealed omental amyloidosis. Here we report an unusual case of multiple myeloma (MM)-associated omental amyloidosis with abdominal ascites and pleural effusion, which can be confused with peritoneal carcinomatosis. The possibility of amyloidosis in the differential diagnosis of abdominal ascites and pleural effusion should be considered.
Amyloidosis is a disease caused by extracellular deposition of fibrous protein in various tissues and organs. It coexists with multiple myeloma in approximately 12%-15% of cases. Omental amyloidosis is rare. We report a 61-year-old woman with omental amyloidosis associated with multiple myeloma. She presented initial symptoms including abdominal ascites and pleural effusion. The patient was diagnosed as having peritoneal carcinomatosis with elevated CA125 level at the first evaluation. Exploratory laparotomy was performed and the histopathological examination revealed omental amyloidosis. Here we report an unusual case of multiple myeloma (MM)-associated omental amyloidosis with abdominal ascites and pleural effusion, which can be confused with peritoneal carcinomatosis. The possibility of amyloidosis in the differential diagnosis of abdominal ascites and pleural effusion should be considered.
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