E-ISSN: 2619-9467

Contents    Cover    Publication Date: 24 Dec 2020
Year 2020 - Volume 30 - Issue 4

Open Access

Peer Reviewed

CASE REPORTS
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Pseudoangiomatous Stromal Hyperplasia-Case Report of a Rare Breast Tumor in a Premenarchal Girl

  
J Clin Obstet Gynecol. 2020;30(4):157-60
DOI: 10.5336/jcog.2020-79475
Article Language: EN
Copyright Ⓒ 2020 by Türkiye Klinikleri. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
ABSTRACT
Pseudoangiomatous stromal hyperplasia is a rare benign breast neoplasm. The exact prevalence of this condition is unknown. According to the literature, it is an extremely uncommon disease in adolescent patients, especially when presenting with a giant mass causing significant breast enlargement. The clinical management of pseudoangiomatous stromal hyperplasia continues to be a controversial issue, however, surgical treatment remains the most accepted when there is an important mass-effect. We report the case of a 12-year-old premenarchal female, referred to our hospital with complaints of a rapidly enlarging left breast mass, of 12cm in diameter, causing a significant breast asymmetry. The ultrasonographic findings were unspecific. The core needle biopsy of the mass was consistent with pseudoangiomatous stromal hyperplasia, consequently, successful surgical excision was performed. This case illustrates a particularly unusual presentation of pseudoangiomatous stromal hyperplasia in a premenarchal adolescent patient, that should be taken into consideration in the differential diagnosis of abrupt breast enlargement.
REFERENCES:
  1. Testori A, Alloisio M, Errico V, Bottoni E, Voulaz E, Fernandez B, et al. Pseudoangiomatous stromal hyperplasia- a benign and rare tumor of the breast in an adolescent: a case report. J Med Case Rep. 2017;11(1):284. [Crossref] [PubMed] [PMC] 
  2. Baker M, Chen H, Latchaw L, Memoli V, Ornvold K. Pseudoangiomatous stromal hyperplasia of the breast in a 10-year-old girl. J Pediatr Surg. 2011;46(8):e27-31.[Crossref] [PubMed] 
  3. Abdelrahman T, Young P, Kozyar O, Davies E, Dojcinov S, Mansel RE. Giant pseudoangiomatous stromal hyperplasia presenting in the breast of a prepubertal child. BMJ Case Rep. 2015;2015:bcr2014206797.[Crossref] [PubMed] [PMC] 
  4. Raj SD, Sahani VG, Adrada BE, Scoggins ME, Albarracin CT, Woodtichartpreecha P, et al. pseudoangiomatous stromal hyperplasia of the breast: multimodality review with pathologic correlation. Curr Probl Diagn Radiol. 2017;46(2):130-5.[Crossref] [PubMed] 
  5. Yoon KH, Koo B, Lee KB, Lee H, Lee J, Kim JY, et al. Optimal treatment of pseudoangiomatous stromal hyperplasia of the breast. Asian J Surg. 2020;43(7):735-41.[Crossref] [PubMed] 
  6. Kurt E, Turanlı S, Markoç F, Berberoğlu U. How to manage pseudoangiomatous stromal hyperplasia: our clinical experience. Turk J Med Sci. 2017;47(5):1410-15.[Crossref] [PubMed] 
  7. Alikhassi A, Ensani F, Omranipour R, Abdollahi A. Bilateral simultaneous pseudoangiomatous stromal hyperplasia of the breasts and axillae: imaging findings with pathological and clinical correlation. Case Rep Radiol. 2016;2016:9084820.[Crossref] [PubMed] [PMC] 
  8. Bowman E, Oprea G, Okoli J, Gundry K, Rizzo M, Gabram-Mendola S, et al. Pseudoangiomatous stromal hyperplasia (PASH) of the breast: a series of 24 patients. Breast J. 2012;18(3):242-7. .[Crossref] [PubMed] [PMC] 
  9. Dai H, Connor C, Cui W, Gatewood J, Fan F. Bilateral diffuse tumorous pseudoangiomatous stromal hyperplasia: a case of bilateral mastectomy in a 29-year-old woman. Case Rep Pathol. 2014;2014:250608.[Crossref] [PubMed] [PMC] 
  10. Kutlutürk K, Usta S, Ünal B, Karadağ N, Akatlı AN. Pseudoangiomatous stromal hyperplasia of the breast presenting as a giant breast tumor: a case report. J Breast Health. 2015;11(1):39-41. .[Crossref] [PubMed] [PMC] 
  11. Tsuda B, Kumaki N, Ishida R, Sakaeda E, Ishii S, Mizuno M, et al. Rare finding of bilateral pseudoangiomatous stromal hyperplasia of the breast: a case report. Tokai J Exp Clin Med. 2019;44(4):73-9.[PubMed]